Effectiveness of mammogram and ultra-sonogram in the diagnosis of breast cancer in asymptomatic women at Central Karnataka

Background: Breast cancer is one of the most common cancers among women around world. Some occult breast can be missed when using ultrasound or mammogram alone. Considering this background, study was performed to highlight improved diagnostic efficacy identifying both and as a combined modality.Methods: A total 150 cases suspected were studied over period 2 years. Ultrasonography, mammography done by two independent radiologists results analyzed. The patients tested for BRCA1/2 gene mutations. Histopathology finally confirm diagnoses.Results: 39 out asymptomatic screened showed that they positive histopathology 38 ultra-sonogram. Cancer prominently diagnosed in age group more than 40 years (92.3%) 82.1% premenopausal stage. High BMI had statistically significant correlation with cancer. 71.7% obese 25.6% overweight individuals. 89.7% from urban population. Detection mutation BRCA 28 BRCA-1 4 BRCA-2 gene.Conclusions: confirms addition ultrasonography improves sensitivity detection women.